EK1202

Human Angiotensinogen/AGT/SerpinA8 ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

分子靶点：AGT, angiotensinogen
种属：人 (Human)
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：100 μL
灵敏度：19.93 pg/mL
检测范围：0.31 ng/mL - 20 ng/mL
回收率：83% - 105%

在售SKU:70-EK1202-48, 70-EK1202-96

¥<\/span>1,600.00<\/bdi><\/span><\/span>","sku":"70-EK1202-48","variation_description":"","variation_id":9874,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"},{"attributes":{"attribute_size":"96T"},"availability_html":"","backorders_allowed":false,"dimensions":{"length":"","width":"","height":""},"dimensions_html":"N\/A","display_price":2650,"display_regular_price":2650,"image":{"title":"ELISA-1.jpg","caption":"","url":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","alt":"","src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","srcset":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg 800w, https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1-768x576.jpg 768w","sizes":"(max-width: 800px) 100vw, 800px","full_src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","full_src_w":800,"full_src_h":600,"gallery_thumbnail_src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1-100x100.jpg","gallery_thumbnail_src_w":100,"gallery_thumbnail_src_h":100,"thumb_src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","thumb_src_w":800,"thumb_src_h":600,"src_w":800,"src_h":600},"image_id":5986,"is_downloadable":false,"is_in_stock":true,"is_purchasable":true,"is_sold_individually":"no","is_virtual":false,"max_qty":"","min_qty":1,"price_html":"¥<\/span>2,650.00<\/bdi><\/span><\/span>","sku":"70-EK1202-96","variation_description":"","variation_id":9875,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"}]">

Size
库存号

描述

文章目录[隐藏]

分子信息
AGT 分子靶点信息概述
AGT 分子靶点综述
- 人 Human AGT 分子靶点信息
- 人 Human AGT靶点分子功能（预测）

商品名	Human Angiotensinogen/AGT/ SerpinA8 ELISA Kit (人血管紧张素原 (AGT) ELISA试剂盒)
检测方法	双抗夹心法
精密度	板内变异系数：4.0% - 4.9%；板间变异系数：3.7%-4.5%
样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	100 μL
灵敏度	19.93 pg/mL
检测范围	0.31 ng/mL - 20 ng/mL
回收率	83% - 105%
平均回收率	0.96
板式	96孔板，可拆
保存	试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。
运输条件	4℃蓝冰运输
组分	包被抗Angiotensinogen/AGT/ SerpinA8单克隆抗体的96孔聚苯乙烯酶标板人Angiotensinogen/AGT/ SerpinA8冻干标准品 Angiotensinogen/AGT/ SerpinA8检测抗体标准品稀释液检测缓冲液(10×) 底物(TMB) 终止液洗液(20×) 封板膜

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人AGT抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、检测样本和辣根过氧化物酶标记的检测抗体，经过孵育，样本中存在的AGT与固相抗体和检测抗体结合。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中AGT的浓度成正比。加入终止液终止反应，在450 nm波长(参考波长570 - 630 nm)测定吸光度值。

Human Angiotensinogen/AGT/ SerpinA8 ELISA Kit (人血管紧张素原 (AGT) ELISA试剂盒) - 标准曲线 — 标准曲线

分子信息

概述人 AGT, angiotensinogen 靶点信息

AGT 分子靶点信息概述

分子名：AGT, angiotensinogen
基因家族：Serpin peptidase inhibitors; Neuropeptides
曾用名：SERPINA8
全称：alpha-1 antiproteinase, antitrypsin; serpin peptidase inhibitor, clade A, member 8

AGT 分子靶点综述

血管紧张素原(AGT)，又称为SerpinA8，是丝氨酸蛋白酶抑制剂家族的一员。AGT是一个α-2-球蛋白，由肝脏组成性产生并释放到血液循环中。AGT是肾素-血管紧张素系统的一个必不可少的组分，是一个有效的血压调节剂。AGT可裂解成3条链：血管紧张素-1、血管紧张素-2和血管紧张素-3。AGT的缺失与原发性高血压及肾小管发育不全相关。一些丝氨酸蛋白酶抑制剂(抗凝血酶、maspin、色素上皮衍生因子和kallistatin)最近已被证明具有抗血管生成活性，表明内皮细胞增殖和迁移的共同机制。AGT和它的肾素裂解产物，在体外和体内可观察到的血浆浓度范围内，也是血管生成抑制剂。

人 Human AGT 分子靶点信息

分子名：AGT, angiotensinogen
别称：
- alpha-1 antiproteinase, antitrypsin
- angiotensin I
- angiotensin II
- angiotensinogen (serine (or cysteine) proteinase inhibitor, clade a (alpha-1 antiproteinase, antitrypsin), member 8)
- angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
- ANHU
- fetal-liver predominant transporter 1
- FLJ92595
- FLJ97926
- hFLT1
- pre-angiotensinogen
- serine (or cysteine) proteinase inhibitor
- serpin A8
- serpin peptidase inhibitor, clade A, member 8
- SERPINA8
基因序列：NCBI_Gene: 183
蛋白序列：UniProtKB: P01019

人 Human AGT靶点分子功能（预测）

Enables angiotensin receptor binding activity; receptor ligand activity; and sodium channel regulator activity. Involved in several processes, including positive regulation of peptidyl-tyrosine phosphorylation; regulation of gene expression; and regulation of signal transduction. Located in extracellular space. Part of collagen-containing extracellular matrix. Implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Biomarker of several diseases, including alcoholic hepatitis; chronic myeloid leukemia; intermediate coronary syndrome; systemic scleroderma (multiple); and type 2 diabetes mellitus.