EK1209

Human CX3CL1/Fractalkine ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

分子靶点：CX3CL1, NTN, CXC3
种属：人 (Human)
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：20 μL
灵敏度：34.45 pg/mL
检测范围：0.16 ng/mL - 10 ng/mL
回收率：80% - 102%

在售SKU:70-EK1209-48, 70-EK1209-96

¥<\/span>1,600.00<\/bdi><\/span><\/span>","sku":"70-EK1209-48","variation_description":"","variation_id":9893,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"},{"attributes":{"attribute_size":"96T"},"availability_html":"","backorders_allowed":false,"dimensions":{"length":"","width":"","height":""},"dimensions_html":"N\/A","display_price":2650,"display_regular_price":2650,"image":{"title":"ELISA-1.jpg","caption":"","url":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","alt":"","src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","srcset":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg 800w, https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1-768x576.jpg 768w","sizes":"(max-width: 800px) 100vw, 800px","full_src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","full_src_w":800,"full_src_h":600,"gallery_thumbnail_src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1-100x100.jpg","gallery_thumbnail_src_w":100,"gallery_thumbnail_src_h":100,"thumb_src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","thumb_src_w":800,"thumb_src_h":600,"src_w":800,"src_h":600},"image_id":5986,"is_downloadable":false,"is_in_stock":true,"is_purchasable":true,"is_sold_individually":"no","is_virtual":false,"max_qty":"","min_qty":1,"price_html":"¥<\/span>2,650.00<\/bdi><\/span><\/span>","sku":"70-EK1209-96","variation_description":"","variation_id":9894,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"}]">

Size
库存号

描述

文章目录[隐藏]

分子信息
CX3CL1 分子靶点信息概述
CX3CL1 分子靶点综述
- 人 Human CX3CL1 分子靶点信息
- 人 Human CX3CL1靶点分子功能（预测）

商品名	Human CX3CL1/Fractalkine ELISA Kit (人趋化因子C-X3-C基序配体1 ELISA试剂盒)
检测方法	双抗夹心法
精密度	板内变异系数：2.1% - 3.6%；板间变异系数：2.6% - 4.4%
样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	20 μL
灵敏度	34.45 pg/mL
检测范围	0.16 ng/mL - 10 ng/mL
回收率	80% - 102%
平均回收率	0.88
板式	96孔板，可拆
保存	试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。
运输条件	4℃蓝冰运输
组分	包被抗CX3CL1单克隆抗体的96孔聚苯乙烯酶标板人CX3CL1冻干标准品 CX3CL1检测抗体标准品稀释液辣根过氧化物酶标记的链霉亲和素检测缓冲液(10×) 底物(TMB) 终止液洗液(20×) 封板膜

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人 CX3CL1 抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的 CX3CL1 与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物 TMB，避光显色。颜色反应的深浅与样本中 CX3CL1 的浓度成正比。加入终止液终止反应，在 450 nm 波长(参考波长 570 - 630 nm)测定吸光度值。

Human CX3CL1/Fractalkine ELISA Kit (人趋化因子C-X3-C基序配体1 ELISA试剂盒) - 标准曲线 — 标准曲线

分子信息

概述人 CX3CL1, NTN, CXC3 靶点信息

CX3CL1 分子靶点信息概述

分子名：CX3CL1, C-X3-C motif chemokine ligand 1
基因家族：Chemokine ligands
别名：NTN; C3Xkine; ABCD-3; CXC3C; CXC3
曾用名：SCYD1
全称：fractalkine; neurotactin; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); chemokine (C-X3-C motif) ligand 1

CX3CL1 分子靶点综述

趋化因子(C-X3-C基序)配体1(CX3CL1)，又名fractalkine，是一个由373个氨基酸组成的大分子细胞因子蛋白，也是CX3C趋化因子家族中唯一一个已知成员。可溶性CX3CL1存在于血清、尿液、脑脊液、羊水和滑液中，主要由血管内皮、平滑肌、神经元和树突状细胞表达。炎性细胞因子如TNF-α和IFN-γ可诱导大多数CX3CL1的表达。CX3CL1是通过与趋化因子受体CX3CR1的相互作用来发挥其粘附和迁移功能。可溶性CX3XL1可强烈趋化T细胞和单核细胞，而细胞结合的趋化因子促进白细胞强有力粘附到活化的内皮细胞上。CX3CL1可能与抗肿瘤活性有关，在消退正常炎症过程如伤口愈合中有重要作用。CX3CL1对某些条件的发病具有促进作用。

人 Human CX3CL1 分子靶点信息

分子名：CX3CL1, C-X3-C motif chemokine ligand 1
别称：
- ABCD-3
- C-X3-C motif chemokine 1
- C3Xkine
- chemokine (C-X3-C motif) ligand 1
- CX3C membrane-anchored chemokine
- CXC3
- CXC3C
- fractalkine
- neurotactin
- NTN
- NTT
- SCYD1
- small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin)
- small inducible cytokine subfamily D (Cys-X3-Cys), member-1
- small-inducible cytokine D1
基因序列：NCBI_Gene: 6376
蛋白序列：UniProtKB: P78423

人 Human CX3CL1靶点分子功能（预测）

Enables signaling receptor binding activity. Involved in several processes, including regulation of cell migration; regulation of gene expression; and regulation of signal transduction. Located in cell surface; extracellular region; and membrane. Is integral component of membrane. Implicated in Cor pulmonale and common cold. Biomarker of several diseases, including chronic fatigue syndrome; myositis (multiple); polyarteritis nodosa; pulmonary hypertension; and rheumatoid arthritis.