Mouse TNF-a ELISA Kit检测试剂盒(酶联免疫吸附法)
¥1,600.00 – ¥10,800.00
- 分子靶点:TNF, TNFA, TNFSF2
- 种属:小鼠 (Mouse)
- 样本类型:血清,血浆,细胞培养上清及其他生物学样本
- 检测样本体积:20 μL
- 灵敏度:0.99 pg/mL
- 检测范围:10.938 pg/mL - 700 pg/mL
- 回收率:81% - 119%
在售SKU:70-EK282-48, 70-EK282-96
描述
背景介绍 | 肿瘤坏死因子α(TNF-α)也称为恶病质素和TNFSF1A,是一种脂肪因子,参与全身的炎症,同时也是刺激急性期反应的细胞因子之一。它主要由活化的巨噬细胞产生,也可由其它类型的细胞分泌,如CD4+淋巴细胞、NK细胞、中性粒细胞、肥大细胞、嗜酸性粒细胞和神经元等。它在免疫应答中具有多种调节功能,还可作为潜在的热原。TNF-α对刺激物(感染因子或组织受损)产生应答后,在全身循环,激活中性粒细胞,改变血管内皮细胞的特性,调控其它组织的代谢活性,以及通过诱导局部凝血作用展现肿瘤杀伤活性。TNF-α在关节组织和其它组织发生炎症的发病机制具有重要作用。最近,越来越多的信息表明TNF-α也参与了AIDS的发病机制。TNF-α的测定对于移植研究也非常有用。 |
检测原理 | 本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗小鼠TNF-α抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体,经过孵育,样本中存在的TNF-α与固相抗体和检测抗体结合。洗涤去除未结合的物质后,加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后,加入显色底物TMB,避光显色。颜色反应的深浅与样本中TNF-α的浓度成正比。加入终止液终止反应,在450 nm波长(参考波长570 - 630 nm)测定吸光度值。 |
组分 | 包被抗TNF-α单克隆抗体的96孔聚苯乙烯酶标板 小鼠TNF-α冻干标准品 TNF-α检测抗体 标准品稀释液 检测缓冲液(10×) 底物(TMB) 终止液 洗液(20×) 封板膜 |
分析类型 | 夹心ELISA |
样本类型 | 血清、血浆,细胞培养上清及其他生物学样本 |
板式 | 96孔板,可拆 |
保存 | 试剂盒未拆开,4℃保存。已拆开,标准品-20℃保存,其它4℃保存。 |
运输条件 | 4℃蓝冰运输 |
样本体积 | 20 μl |
灵敏度 | 0.99 pg/ml |
标曲图 | |
标准曲线范围 | 10.938 - 700 pg/ml |
回收率范围 | 81 %-119 % |
平均回收率 | 1.01 |
板间变异系数 | 3.8 % - 5.1 % |
板内变异系数 | 3.1 % - 4.5 % |
分子信息
TNF 分子靶点信息概述
- 分子名:TNF, tumor necrosis factor
- 基因家族:Tumor necrosis factor superfamily
- 别名:TNFSF2; DIF; TNF-alpha
- 曾用名:TNFA
- 全称:TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2)
TNF 分子靶点综述
TNF-α 为单核细胞、巨噬细胞、中性粒细胞、NK 细胞和 CD4+T 细胞产生的 17 kDa 细胞因子。它在免疫应答中具有多种调节功能,还可作为潜在的热原。TNF-α对刺激物(感染因子或组织受损)产生应答后,在全身循环,激活中性粒细胞,改变血管内皮细胞的特性,调控其它组织的代谢活性,以及通过诱导局部凝血作用展现肿瘤杀伤活性。TNF-α 在关节组织和其它组织发生炎症的发病机制具有重要作用。
小鼠 Mouse Tnf 分子靶点信息
- 分子名:Tnf, tumor necrosis factor
- 别称:
- DIF
- TNF alpha
- TNF-alpha
- Tnfa
- TNFalpha
- Tnfsf1a
- tumor necrosis factor-alpha
- tumor necrosis factor, alpha
- 基因序列:NCBI_Gene: 21926
- 蛋白序列:
小鼠 Mouse Tnf 靶点分子功能(预测)
Enables cytokine activity; protease binding activity; and tumor necrosis factor receptor binding activity. Involved in several processes, including endothelial cell apoptotic process; positive regulation of cell communication; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including apoptotic signaling pathway; positive regulation of intracellular signal transduction; and regulation of gene expression. Located in several cellular components, including external side of plasma membrane; phagocytic cup; and recycling endosome. Is expressed in several structures, including alimentary system; brain; integumental system; lung; and reproductive system. Used to study several diseases, including autoimmune disease (multiple); congestive heart failure; heart valve disease (multiple); idiopathic pulmonary fibrosis; and spondyloarthropathy. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); lung disease (multiple); and skin disease (multiple). Orthologous to human TNF (tumor necrosis factor).
引用文献
文章目录[隐藏]
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- Tumor-Selective Activation of Toll-Like Receptor 7/8 Agonist Nano-Immunomodulator Generates Safe Anti-Tumor Immune Responses upon Systemic Administration 
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- An Injectable Hydrogel Reshaping Adenosinergic Axis for Cancer Therapy 
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- The Immunoenhancement Effects of Polyethylenimine-Modified Chinese Yam Polysaccharide-Encapsulated Plga Nanoparticles as an Adjuvant 
- Intravenous Injection of the Oncolytic Virus M1 Awakens Antitumor T Cells and Overcomes Resistance to Checkpoint Blockade 
- In Situ Transforming Rna Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy 
- Immunomodulatory Effects of Fucosylated Chondroitin Sulfate from Stichopus Chloronotus on Raw 264.7 Cells 
- Administration Routes of Polyethylenimine-Coated Plga Nanoparticles Encapsulating Angelica Sinensis Polysaccharide Vaccine Delivery System Affect Immune Responses 
- Polylysine-Bilirubin Conjugates Maintain Functional Islets and Promote M2 Macrophage Polarization 
- Genipin-Crosslinked Human Serum Albumin Coating Using a Tannic Acid Layer for Enhanced Oral Administration of Curcumin in the Treatment of Ulcerative Colitis 
- Vesicle-Mediated Dendritic Cell Activation in Acinetobacter Baumannii Clinical Isolate, Which Contributes to Th2 Response 
- Paclitaxel Alleviated Sepsis-Induced Acute Lung Injury by Activating Muc1 and Suppressing Tlr-4/Nf-Κb Pathway 
- Tri-component programmable nanoregulator with Three-pronged penetration boosts immunotherapy of Triple-Negative breast cancer 
- Blockage of the IDO1 pathway by charge-switchable nanoparticles amplifies immunogenic cell death for enhanced cancer immunotherapy 
- Potential shared therapeutic and hepatotoxic mechanisms of Tripterygium wilfordii polyglycosides treating three kinds of autoimmune skin diseases by regulating IL-17 signaling pathway and Th17 cell differentiation 
- Biomimetic Lipopolysaccharide-Free Bacterial Outer Membrane-Functionalized Nanoparticles for Brain-Targeted Drug Delivery 
- A Network Pharmacology-Based Investigation to the Pharmacodynamic Material Basis and Mechanisms of the Anti-Inflammatory and Anti-Viral Effect of Isatis Indigotica 
- Separable Microneedle Patch to Protect and Deliver DNA Nanovaccines against Covid-19 
- Molecular Mechanisms Underlying Macrophage Immunomodulatory Activity of Rubus Chingii Hu Polysaccharides 
- Entrapment of Macrophage-Target Nanoparticles by Yeast Microparticles for Rhein Delivery in Ulcerative Colitis Treatment 
- Oral Core-Shell Nanoparticles Embedded in Hydrogel Microspheres for the Efficient Site-Specific Delivery of Magnolol and Enhanced Antiulcerative Colitis Therapy 
- A Small and Highly Sensitive Red/Far-Red Optogenetic Switch for Applications in Mammals 
- Toxoplasma Gondii Sag1 Targeting Host Cell S100a6 for Parasite Invasion and Host Immunity 
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- Polarization of Tumor-Associated Macrophages by Nanoparticle-Loaded Escherichia Coli Combined with Immunogenic Cell Death for Cancer Immunotherapy 
- Platelet-Armored Nanoplatform to Harmonize Janus-Faced Ifn-γ against Tumor Recurrence and Metastasis 
- Capsaicin Protects against Lipopolysaccharide-Induced Acute Lung Injury through the Hmgb1/Nf-Κb and Pi3k/Akt/Mtor Pathways 
- Syndecan-1 Shedding by Matrix Metalloproteinase-9 Signaling Regulates Alveolar Epithelial Tight Junction in Lipopolysaccharide-Induced Early Acute Lung Injury 
- A Clinically Acceptable Strategy for Sensitizing Anti-Pd-1 Treatment by Hypoxia Relief 
- Protective Effects of Chitosan-Bilirubin Nanoparticles against Ethanol-Induced Gastric Ulcers 
- Bacterium-Mimicking Vector with Enhanced Adjuvanticity for Cancer Immunotherapy and Minimized Toxicity 
- Targeting macrophagic 17β-HSD7 by fenretinide for the treatment of nonalcoholic fatty liver disease 
- Peucedanum praeruptorum Dunn polysaccharides regulate macrophage inflammatory response through TLR2/TLR4-mediated MAPK and NF-κB pathways 
- Macrophage activation by exopolysaccharides from Streptococcus thermophilus fermented milk through TLRs-mediated NF-κB and MAPK pathways 
- Comparison of CD146 +/- mesenchymal stem cells in improving premature ovarian failure 
- The activation effects of fucoidan from sea cucumber Stichopus chloronotus on RAW264.7 cells via TLR2/4-NF-κB pathway and its structure-activity relationship 
- Spatiotemporally Controllable Distribution of Combination Therapeutics in Solid Tumors by Dually Modified Bacteria 
- Non-peptidyl non-covalent cathepsin C inhibitoEEr bearing a unique thiophene-substituted pyridine: Design, structure-activity relationship and anti-inflammatory activity in vivo 
- Immunosuppressive activity is attenuated by Astragalus polysaccharides through remodeling the gut microenvironment in melanoma mice 
- Uncovering the Metabolic Mechanism of Salidroside Alleviating Microglial Hypoxia Inflammation Based on Microfluidic Chip-Mass Spectrometry 
- Red Blood Cell Membrane-Camouflaged PLGA Nanoparticles Loaded With Basic Fibroblast Growth Factor for Attenuating Sepsis-Induced Cardiac Injury 
- Overcoming resistance to oncolytic virus M1 by targeting PI3K-γ in tumor-associated myeloid cells 
- Two glycoproteins from medicinal insect Periplaneta americana (L.) promote diabetic wound healing via macrophage polarization modulation 
- Ionic liquid-based non-releasing antibacterial, anti-inflammatory, high-transparency hydrogel coupled with electrical stimulation for infected diabetic wound healing 
- Sprayable nanodrug-loaded hydrogels with enzyme-catalyzed semi-inter penetrating polymer network (Semi-IPN) for solar dermatitis 
- Osteoimmune reaction caused by a novel silicocarnotite bioceramic promoting osteogenesis through the MAPK pathway 
- Effect of Polysaccharides from Bletilla striata on the Healing of Dermal Wounds in Mice 
- pH Switchable Nanoplatform for In Vivo Persistent Luminescence Imaging and Precise Photothermal Therapy of Bacterial Infection 
- Neutrophil membrane-coated therapeutic liposomes for targeted treatment in acute lung injury 
- An Integration of Network Pharmacology and Experimental Verification to Investigate the Mechanism of Guizhi to Treat Nephrotic Syndrome 
- Tigit Negatively Regulates Inflammation by Altering Macrophage Phenotype 
- Mir-30a Positively Regulates the Inflammatory Response of Microglia in Experimental Autoimmune Encephalomyelitis 
- Erythrocyte Membrane-Enveloped Polymeric Nanoparticles as Nanovaccine for Induction of Antitumor Immunity against Melanoma 
- Anti-Inflammatory Effects of Cajaninstilbene Acid and Its Derivatives 
- Schisantherin a Alleviated Alcohol-Induced Liver Injury by the Regulation of Alcohol Metabolism and Nf-Kb Pathway 
- Anti-Inflammatory Effect of the Six Compounds Isolated from Nauclea Officinalis Pierrc Ex Pitard, and Molecular Mechanism of Strictosamide Via Suppressing the Nf-Κb and Mapk Signaling Pathway in Lps-Induced Raw 264.7 Macrophages 
- The B-Raf(V600e) Inhibitor Dabrafenib Selectively Inhibits Rip3 and Alleviates Acetaminophen-Induced Liver Injury 
- Genetic Elimination of Nrf2 Aggravates Secondary Complications except for Vasospasm after Experimental Subarachnoid Hemorrhage in Mice 
- Curcumin Ameliorates Asthmatic Airway Inflammation by Activating Nuclear Factor-E2-Related Factor 2/Haem Oxygenase (Ho)-1 Signalling Pathway 
- Heparin Inhibits Lipopolysaccharide-Induced Inflammation Via Inducing Caveolin-1 and Activating the P38/Mitogen-Activated Protein Kinase Pathway in Murine Peritoneal Macrophages 
- Inflammasome-Independent Role of Nlrp12 in Suppressing Colonic Inflammation Regulated by Blimp-1 
- Antimicrobial Peptide Cathelicidin-Bf Prevents Intestinal Barrier Dysfunction in a Mouse Model of Endotoxemia 
- Anti-Inflammatory Effect of Rosa Rugosa Flower Extract in Lipopolysaccharide-Stimulated Raw264.7 Macrophages 
- Design, Synthesis and Anti-Inflammatory Evaluation of Novel 5-Benzylidene-3,4-Dihalo-Furan-2-One Derivatives 
- Enhanced Antitumor Activity of Gemcitabine by Polysaccharide-Induced Nk Cell Activation and Immune Cytotoxicity Reduction in Vitro/Vivo 
- The Mechanism of Hepatoprotective Effect of Sesquiterpene Rich Fraction from Cichorum Glandulosum Boiss. Et Huet on Immune Reaction-Induced Liver Injury in Mice 
- Hmgb1-Tlr4-Il23-Il17a Axis Promotes Paraquat-Induced Acute Lung Injury by Mediating Neutrophil Infiltration in Mice 
- Comparative Studies of Macrophage-Biased Responses in Mice to Infection with Toxoplasma Gondii Toxodb #9 Strains of Different Virulence Isolated from China 
- Nauclea Officinalis Inhibits Inflammation in Lps-Mediated Raw 264.7 Macrophages by Suppressing the Nf-Κb Signaling Pathway 
- Cytochrome P450 (Cyp) Epoxygenases as Potential Targets in the Management of Impaired Diabetic Wound Healing 
- A High-Fat, High-Protein Diet Attenuates the Negative Impact of Casein-Induced Chronic Inflammation on Testicular Steroidogenesis and Sperm Parameters in Adult Mice 
- Ginsenoside Rg1 Attenuates the Inflammatory Response in Dss-Induced Mice Colitis 
- Use of Immune Modulation by Human Adipose-Derived Mesenchymal Stem Cells to Treat Experimental Arthritis in Mice 
- 细胞培养上清
Multifunctional biomimetic nanoplatform based on photodynamic therapy and DNA repair intervention for the synergistic treatment of breast cancer 
- 组织匀浆 细胞裂解液 血清
ASPS Exhibits Anti-Rheumatic Effects by Reprogramming Gut Microbiota and Increasing Serum γ-Glutamylcysteine Level 
- 血清
Tumor-Selective Activation of Toll-Like Receptor 7/8 Agonist Nano-Immunomodulator Generates Safe Anti-Tumor Immune Responses upon Systemic Administration 
- RAW 264.7 人肺癌细胞 A549 支气管肺泡灌洗液 BALF 细胞培养上清
Melatonin attenuates LPS-induced pyroptosis in acute lung injury by inhibiting NLRP3-GSDMD pathway via activating Nrf2/HO-1 signaling axis 
- 组织匀浆 细胞培养上清 血清
A Lysosome-Activated Tetrahedral Nanobox for Encapsulated siRNA Delivery 
- 组织匀浆 肿瘤 血清
An Injectable Hydrogel Reshaping Adenosinergic Axis for Cancer Therapy 
- 海马体 组织匀浆
Multifunctional Nanostructure Rap-Rl Rescues Alzheimer's Cognitive Deficits through Remodeling the Neurovascular Unit 
- 细胞培养上清 血清
The Immunoenhancement Effects of Polyethylenimine-Modified Chinese Yam Polysaccharide-Encapsulated Plga Nanoparticles as an Adjuvant 
- 细胞培养上清
Intravenous Injection of the Oncolytic Virus M1 Awakens Antitumor T Cells and Overcomes Resistance to Checkpoint Blockade 
- 血清
In Situ Transforming Rna Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy 
- RAW 264.7 细胞培养上清
Immunomodulatory Effects of Fucosylated Chondroitin Sulfate from Stichopus Chloronotus on Raw 264.7 Cells 
- 组织匀浆 脾脏 血清
Administration Routes of Polyethylenimine-Coated Plga Nanoparticles Encapsulating Angelica Sinensis Polysaccharide Vaccine Delivery System Affect Immune Responses 
- 细胞培养上清
Polylysine-Bilirubin Conjugates Maintain Functional Islets and Promote M2 Macrophage Polarization 
- 组织匀浆 结肠
Genipin-Crosslinked Human Serum Albumin Coating Using a Tannic Acid Layer for Enhanced Oral Administration of Curcumin in the Treatment of Ulcerative Colitis 
- 血清
Vesicle-Mediated Dendritic Cell Activation in Acinetobacter Baumannii Clinical Isolate, Which Contributes to Th2 Response 
- 支气管肺泡灌洗液 BALF 细胞培养上清 血清
Paclitaxel Alleviated Sepsis-Induced Acute Lung Injury by Activating Muc1 and Suppressing Tlr-4/Nf-Κb Pathway 
- 血清
Tri-component programmable nanoregulator with Three-pronged penetration boosts immunotherapy of Triple-Negative breast cancer 
- 组织匀浆 肿瘤
Blockage of the IDO1 pathway by charge-switchable nanoparticles amplifies immunogenic cell death for enhanced cancer immunotherapy 
- 皮肤 皮肤损伤组织 组织匀浆 血清
Potential shared therapeutic and hepatotoxic mechanisms of Tripterygium wilfordii polyglycosides treating three kinds of autoimmune skin diseases by regulating IL-17 signaling pathway and Th17 cell differentiation 
- 组织匀浆 脑脊液 脾脏 血清
Biomimetic Lipopolysaccharide-Free Bacterial Outer Membrane-Functionalized Nanoparticles for Brain-Targeted Drug Delivery 
- RAW 264.7 细胞培养上清
A Network Pharmacology-Based Investigation to the Pharmacodynamic Material Basis and Mechanisms of the Anti-Inflammatory and Anti-Viral Effect of Isatis Indigotica 
- 血清
Separable Microneedle Patch to Protect and Deliver DNA Nanovaccines against Covid-19 
- 细胞培养上清
Molecular Mechanisms Underlying Macrophage Immunomodulatory Activity of Rubus Chingii Hu Polysaccharides 
- 组织匀浆
Entrapment of Macrophage-Target Nanoparticles by Yeast Microparticles for Rhein Delivery in Ulcerative Colitis Treatment 
- 组织匀浆 细胞培养上清 结肠
Oral Core-Shell Nanoparticles Embedded in Hydrogel Microspheres for the Efficient Site-Specific Delivery of Magnolol and Enhanced Antiulcerative Colitis Therapy 
- 血清
A Small and Highly Sensitive Red/Far-Red Optogenetic Switch for Applications in Mammals 
- 细胞培养上清
Toxoplasma Gondii Sag1 Targeting Host Cell S100a6 for Parasite Invasion and Host Immunity 
- 血清
Living Bacterial Hydrogels for Accelerated Infected Wound Healing 
- 组织匀浆
Genome-Editing Prodrug: Targeted Delivery and Conditional Stabilization of Crispr-Cas9 for Precision Therapy of Inflammatory Disease 
- 细胞培养上清
Polarization of Tumor-Associated Macrophages by Nanoparticle-Loaded Escherichia Coli Combined with Immunogenic Cell Death for Cancer Immunotherapy 
- 组织培养上清
Platelet-Armored Nanoplatform to Harmonize Janus-Faced Ifn-γ against Tumor Recurrence and Metastasis 
- 支气管肺泡灌洗液 BALF 组织匀浆
Capsaicin Protects against Lipopolysaccharide-Induced Acute Lung Injury through the Hmgb1/Nf-Κb and Pi3k/Akt/Mtor Pathways 
- 支气管肺泡灌洗液 BALF 血清
Syndecan-1 Shedding by Matrix Metalloproteinase-9 Signaling Regulates Alveolar Epithelial Tight Junction in Lipopolysaccharide-Induced Early Acute Lung Injury 
- 全血 组织匀浆 肿瘤 脾脏
A Clinically Acceptable Strategy for Sensitizing Anti-Pd-1 Treatment by Hypoxia Relief 
- 组织匀浆 细胞培养上清
Protective Effects of Chitosan-Bilirubin Nanoparticles against Ethanol-Induced Gastric Ulcers 
- 组织匀浆 细胞培养上清 肿瘤 血清
Bacterium-Mimicking Vector with Enhanced Adjuvanticity for Cancer Immunotherapy and Minimized Toxicity 
- 组织匀浆 肺
Targeting macrophagic 17β-HSD7 by fenretinide for the treatment of nonalcoholic fatty liver disease 
- 细胞培养上清
Peucedanum praeruptorum Dunn polysaccharides regulate macrophage inflammatory response through TLR2/TLR4-mediated MAPK and NF-κB pathways 
- 细胞培养上清
Macrophage activation by exopolysaccharides from Streptococcus thermophilus fermented milk through TLRs-mediated NF-κB and MAPK pathways 
- 血清
Comparison of CD146 +/- mesenchymal stem cells in improving premature ovarian failure 
- RAW 264.7 细胞培养上清
The activation effects of fucoidan from sea cucumber Stichopus chloronotus on RAW264.7 cells via TLR2/4-NF-κB pathway and its structure-activity relationship 
- 血清
Spatiotemporally Controllable Distribution of Combination Therapeutics in Solid Tumors by Dually Modified Bacteria 
- 组织匀浆 肺 血清
Non-peptidyl non-covalent cathepsin C inhibitoEEr bearing a unique thiophene-substituted pyridine: Design, structure-activity relationship and anti-inflammatory activity in vivo 
- 血清
Immunosuppressive activity is attenuated by Astragalus polysaccharides through remodeling the gut microenvironment in melanoma mice 
- 细胞培养上清
Uncovering the Metabolic Mechanism of Salidroside Alleviating Microglial Hypoxia Inflammation Based on Microfluidic Chip-Mass Spectrometry 
- 全血 心组织 组织匀浆 细胞培养上清
Red Blood Cell Membrane-Camouflaged PLGA Nanoparticles Loaded With Basic Fibroblast Growth Factor for Attenuating Sepsis-Induced Cardiac Injury 
- 细胞培养上清
Overcoming resistance to oncolytic virus M1 by targeting PI3K-γ in tumor-associated myeloid cells 
- RAW 264.7 细胞培养上清
Two glycoproteins from medicinal insect Periplaneta americana (L.) promote diabetic wound healing via macrophage polarization modulation 
- 细胞培养上清
Ionic liquid-based non-releasing antibacterial, anti-inflammatory, high-transparency hydrogel coupled with electrical stimulation for infected diabetic wound healing 
- 细胞培养上清
Sprayable nanodrug-loaded hydrogels with enzyme-catalyzed semi-inter penetrating polymer network (Semi-IPN) for solar dermatitis 
- RAW 264.7 细胞培养上清
Osteoimmune reaction caused by a novel silicocarnotite bioceramic promoting osteogenesis through the MAPK pathway 
- 血清
Effect of Polysaccharides from Bletilla striata on the Healing of Dermal Wounds in Mice 
- 血清
pH Switchable Nanoplatform for In Vivo Persistent Luminescence Imaging and Precise Photothermal Therapy of Bacterial Infection 
- 细胞培养上清
Neutrophil membrane-coated therapeutic liposomes for targeted treatment in acute lung injury 
- 细胞培养上清
An Integration of Network Pharmacology and Experimental Verification to Investigate the Mechanism of Guizhi to Treat Nephrotic Syndrome 
Tigit Negatively Regulates Inflammation by Altering Macrophage Phenotype 
Mir-30a Positively Regulates the Inflammatory Response of Microglia in Experimental Autoimmune Encephalomyelitis 
Erythrocyte Membrane-Enveloped Polymeric Nanoparticles as Nanovaccine for Induction of Antitumor Immunity against Melanoma 
Anti-Inflammatory Effects of Cajaninstilbene Acid and Its Derivatives 
Schisantherin a Alleviated Alcohol-Induced Liver Injury by the Regulation of Alcohol Metabolism and Nf-Kb Pathway 
- RAW 264.7
Anti-Inflammatory Effect of the Six Compounds Isolated from Nauclea Officinalis Pierrc Ex Pitard, and Molecular Mechanism of Strictosamide Via Suppressing the Nf-Κb and Mapk Signaling Pathway in Lps-Induced Raw 264.7 Macrophages 
The B-Raf(V600e) Inhibitor Dabrafenib Selectively Inhibits Rip3 and Alleviates Acetaminophen-Induced Liver Injury 
Genetic Elimination of Nrf2 Aggravates Secondary Complications except for Vasospasm after Experimental Subarachnoid Hemorrhage in Mice 
- RAW 264.7
Curcumin Ameliorates Asthmatic Airway Inflammation by Activating Nuclear Factor-E2-Related Factor 2/Haem Oxygenase (Ho)-1 Signalling Pathway 
Heparin Inhibits Lipopolysaccharide-Induced Inflammation Via Inducing Caveolin-1 and Activating the P38/Mitogen-Activated Protein Kinase Pathway in Murine Peritoneal Macrophages 
Inflammasome-Independent Role of Nlrp12 in Suppressing Colonic Inflammation Regulated by Blimp-1 
- RAW 264.7
Antimicrobial Peptide Cathelicidin-Bf Prevents Intestinal Barrier Dysfunction in a Mouse Model of Endotoxemia 
- RAW 264.7
Anti-Inflammatory Effect of Rosa Rugosa Flower Extract in Lipopolysaccharide-Stimulated Raw264.7 Macrophages 
Design, Synthesis and Anti-Inflammatory Evaluation of Novel 5-Benzylidene-3,4-Dihalo-Furan-2-One Derivatives 
Enhanced Antitumor Activity of Gemcitabine by Polysaccharide-Induced Nk Cell Activation and Immune Cytotoxicity Reduction in Vitro/Vivo 
The Mechanism of Hepatoprotective Effect of Sesquiterpene Rich Fraction from Cichorum Glandulosum Boiss. Et Huet on Immune Reaction-Induced Liver Injury in Mice 
Hmgb1-Tlr4-Il23-Il17a Axis Promotes Paraquat-Induced Acute Lung Injury by Mediating Neutrophil Infiltration in Mice 
Comparative Studies of Macrophage-Biased Responses in Mice to Infection with Toxoplasma Gondii Toxodb #9 Strains of Different Virulence Isolated from China 
- RAW 264.7
Nauclea Officinalis Inhibits Inflammation in Lps-Mediated Raw 264.7 Macrophages by Suppressing the Nf-Κb Signaling Pathway 
Cytochrome P450 (Cyp) Epoxygenases as Potential Targets in the Management of Impaired Diabetic Wound Healing 
A High-Fat, High-Protein Diet Attenuates the Negative Impact of Casein-Induced Chronic Inflammation on Testicular Steroidogenesis and Sperm Parameters in Adult Mice 
Ginsenoside Rg1 Attenuates the Inflammatory Response in Dss-Induced Mice Colitis 
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