EK109

Human IL-9 ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

分子靶点：IL9, IL-9, P40, HP40
种属：人 (Human)
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：100 μL
灵敏度：0.06 pg/mL
检测范围：7.81 pg/mL - 500 pg/mL
回收率：80% - 117%

在售SKU:70-EK109-48, 70-EK109-96, 人白细胞介素9, 白细胞介素9, 白细胞介素, 人, 白介素, 9

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Size
库存号

描述

文章目录[隐藏]

分子信息
IL9 分子靶点信息概述
IL9 分子靶点综述
- 人 Human IL9 分子靶点信息
- 人 Human IL9靶点分子功能（预测）

商品名	Human IL-9 ELISA Kit (人白细胞介素9ELISA 试剂盒)
检测方法	双抗夹心法
精密度	板内变异系数：2.9% - 3.1%；板间变异系数：3.3% - 5.7%
样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	100 μL
灵敏度	0.06 pg/mL
检测范围	7.81 pg/mL - 500 pg/mL
回收率	80% - 117%
平均回收率	1.04
板式	96孔板，可拆
保存	试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。
运输条件	4℃蓝冰运输
组分	包被抗IL-9单克隆抗体的96孔聚苯乙烯酶标板人IL-9冻干标准品 IL-9 检测抗体标准品稀释液辣根过氧化物酶标记的链霉亲和素检测缓冲液(10×) 底物(TMB) 终止液洗液(20×) 封板膜

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人IL-9抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的IL-9与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中IL-9的浓度成正比。加入终止液终止反应，在450 nm波长(参考波长570 - 630 nm)测定吸光度值。

Human IL-9 ELISA Kit (人白细胞介素9ELISA 试剂盒) - 标准曲线 — 标准曲线

分子信息

概述人 IL9, IL-9, P40, HP40 靶点信息

IL9 分子靶点信息概述

分子名：IL9, interleukin 9
基因家族：Interleukins
别名：IL-9; HP40; P40
全称：p40 T-cell and mast cell growth factor; T-cell growth factor p40; p40 cytokine; homolog of mouse T cell and mast cell growth factor 40

IL9 分子靶点综述

白细胞介素9(IL-9)是一个分子量为14kDa的糖基化蛋白，包含10个参与二硫键连接的半胱氨酸残基。它是由T细胞特别是CD4+辅助性细胞产生的细胞因子，可调节多种造血细胞。该细胞因子刺激细胞增殖、阻止细胞凋亡。它是通过与IL-9受体结合起作用的，可激活不同的信号转导及激活(STAT)蛋白，从而参与多种生物过程。编码该细胞因子的基因已被确定为哮喘的候选基因。小鼠模型的哮喘遗传研究表明，这种细胞因子是支气管高反应发病机制的一个决定性因素。IL-9介导的自分泌环的存在暗示着一些恶性肿瘤如霍奇金病的存在。IL-9由李-斯二氏细胞、霍奇金淋巴瘤细胞和一些大型再生障碍性淋巴瘤细胞表达，而非霍奇金淋巴瘤和外周T细胞淋巴瘤不表达。

人 Human IL9 分子靶点信息

分子名：IL9, interleukin 9
别称：
- cytokine P40
- homolog of mouse T cell and mast cell growth factor 40
- HP40
- IL-9
- interleukin-9
- P40
- p40 cytokine
- p40 T-cell and mast cell growth factor
- T-cell growth factor p40
基因序列：NCBI_Gene: 3578
蛋白序列：UniProtKB: P15248

人 Human IL9靶点分子功能（预测）

Predicted to enable cytokine activity and interleukin-9 receptor binding activity. Predicted to be involved in positive regulation of interleukin-5 production. Predicted to act upstream of or within several processes, including B cell activation; regulation of cellular protein metabolic process; and regulation of receptor signaling pathway via JAK-STAT. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Implicated in asthma and respiratory syncytial virus infectious disease. Biomarker of COVID-19; asthma; cystic fibrosis; lung disease (multiple); and rhinitis.