F11062P01

Anti-Human CD62P, FITC (Clone:AK-4) (新品)

¥720.00 – ¥1,584.00

说明书

分子靶点：SELP, CD62P, GRMP
种属：人 (Human)
标记：FITC
亚型：Mouse IgG1, κ
克隆号：AK-4

在售SKU, 70-AH062P01-20, 70-AH062P01-50, 70-AH062P01-100, AH062P01, 70-F11062P01-25, 70-F11062P01-100

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Size
库存号

描述

文章目录[隐藏]

结果示例
分子信息
SELP 分子靶点信息概述
SELP 分子靶点综述
- 人 Human SELP 分子靶点信息
- 人 Human SELP靶点分子功能（预测）

商品名	Anti-Human CD62P, FITC (Clone:AK-4)
靶点	SELP, CD62P, GRMP
标记	FITC
仪器	适用488nm激光器的流式细胞仪
亚型	Mouse IgG1, κ
克隆号	AK-4
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 人外周血染色 Anti-Human CD62P, FITC (F11062P01)(实线) 和 Mouse IgG1 κ Isotype Control FITC(CMG101) (虚线)的结果。以血小板设门进行分析。

分子信息

概述人 SELP, CD62P, GRMP 靶点信息

SELP 分子靶点信息概述

分子名：SELP, selectin P
基因家族：CD molecules; Selectins; Sushi domain containing; C-type lectin domain containing
别名：CD62; PSEL; PADGEM; GMP140; CD62P
曾用名：GRMP
全称：antigen CD62; granule membrane protein 140kDa; selectin P (granule membrane protein 140kD, antigen CD62); selectin P (granule membrane protein 140kDa, antigen CD62)

SELP 分子靶点综述

CD62P 是一种 140kDa 跨膜糖蛋白，也称为 P-Selectin。P-Selectin被储存在血小板的 α 颗粒和内皮细胞的 Weibel-Palade 小体中，并在激活后迅速转运到质膜。在炎症反应中，P-Selectin 被认为介导中性粒细胞和单核细胞与内皮的初始粘附相互作用；在止血过程中，活化的血小板与中性粒细胞和单核细胞相互作用。

人 Human SELP 分子靶点信息

分子名：SELP, selectin P
别称：
- CD62
- CD62 antigen-like family member P
- CD62P
- FLJ45155
- GMP-140
- GMP140
- granule membrane protein 140
- granule membrane protein 140kDa
- granulocyte membrane protein
- GRMP
- LECAM3
- leukocyte-endothelial cell adhesion molecule 3
- P-selectin
- PADGEM
- platelet activation dependent granule-external membrane protein
- platelet alpha-granule membrane protein
- PSEL
- selectin P (granule membrane protein 140kDa, antigen CD62)
基因序列：NCBI_Gene: 6403
蛋白序列：UniProtKB: P16109

人 Human SELP靶点分子功能（预测）

Enables several functions, including fucose binding activity; heparin binding activity; and lipopolysaccharide binding activity. Involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; calcium-mediated signaling using intracellular calcium source; and leukocyte tethering or rolling. Located in external side of plasma membrane; extracellular space; and platelet alpha granule membrane. Is integral component of plasma membrane. Implicated in atopic dermatitis and myocardial infarction. Biomarker of several diseases, including Kawasaki disease; autoimmune disease (multiple); coronary artery disease (multiple); obesity; and type 2 diabetes mellitus.

操作步骤

文章目录[隐藏]

使用方法
注意事项
FCM流式检测常见问题
查看更多FCM流式检测相关问题

下载本产品说明书

使用方法

全血样本：在流式管中加入 100μl 枸橼酸钠(ACD)抗凝血，与 2 ml 洗液(PBS, pH7.2 - 7.4，含 0.35% BSA和 13 mM 枸橼酸钠)混匀，300 × g 离心 5 分钟，弃上清，洗涤 2 次。用 100 μl 洗液重悬沉淀(通常洗涤后残留的液体量就已足够)。加入 10 μl 凝血酶溶液(100U/ml)，于 37℃孵育 5 分钟。孵育结束后，无需洗涤，直接加入 5 μl Anti-Human CD62P, FITC 和其他抗体，震荡混匀，室温避光孵育 15 分钟。加入 2 ml 1%多聚甲醛，震荡混匀，避光孵育 15 分钟。300 × g 离心 5分钟，弃上清。每管加入 2 ml 洗液，震荡混匀，300 × g 离心 5 - 10 分钟，弃上清，加入 500μl洗液重悬，上机检测。
实验中，可对抗体进行优化滴定以获得最佳效果。

注意事项

请在使用本产品前仔细阅读说明书。本产品仅用于科研，不可用于诊断。
为了您的安全和健康，请穿戴实验防护服、手套、口罩等必要的防护装备。
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Anti-Human CD62P, FITC (Clone:AK-4) (新品)

描述

结果示例

分子信息

SELP 分子靶点信息概述

SELP 分子靶点综述

人 Human SELP 分子靶点信息

人 Human SELP靶点分子功能（预测）

操作步骤

使用方法

注意事项

FCM流式检测常见问题

查看更多FCM流式检测相关问题

引用文献

评价

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Anti-Human CD62P, FITC (Clone:AK-4) (新品)

描述

结果示例

分子信息

SELP 分子靶点信息概述

SELP 分子靶点综述

人 Human SELP 分子靶点信息

人 Human SELP靶点分子功能（预测）

操作步骤

使用方法

注意事项

FCM流式检测常见问题

引用文献

评价

相关产品