EK1194

Human OSMR ELISA Kit 检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

分子靶点：OSMR
种属：人 (Human)
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：血清血浆：20 μL；细胞培养上清：100 μL
灵敏度：35.9 pg/mL
检测范围：0.16 ng/mL - 10 ng/mL
回收率：81% - 112%

在售SKU:70-EK1194-48, 70-EK1194-96,EK1194，70-EK1194/2-48, 70-EK1194/2-96,EK1194/2

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Size
库存号

描述

文章目录[隐藏]

分子信息
OSMR 分子靶点信息概述
OSMR 分子靶点综述
- 人 Human OSMR 分子靶点信息
- 人 Human OSMR靶点分子功能（预测）

商品名	Human OSMR ELISA Kit 检测试剂盒（酶联免疫吸附法）
检测方法	双抗夹心法
精密度	板内变异系数：3.4% - 4.3%；板间变异系数：5.2% - 7.0%
样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	血清血浆：20 μL；细胞培养上清：100 μL
灵敏度	35.9 pg/mL
检测范围	0.16 ng/mL - 10 ng/mL
回收率	81% - 112%
平均回收率	0.99
板式	96孔板，可拆
保存	试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。
运输条件	4℃蓝冰运输
组分	酶标板标准品检测抗体标准品稀释液检测缓冲液(10×) 底物(TMB) 终止液洗液(20×) 封板膜

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人 OSMR 抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和辣根过氧化物酶标记检测抗体，经过孵育，样本中存在的 OSMR 与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入显色底物 TMB，避光显色。颜色反应的深浅与样本中 OSMR 的浓度成正比。加入终止液终止反应，在 450nm 波长(参考波长 570 - 630 nm)测定吸光度值。

Human OSMR ELISA Kit 检测试剂盒 - 标准曲线 — 标准曲线

分子信息

概述人 OSMR, oncostatin M receptor 靶点信息

OSMR 分子靶点信息概述

分子名：OSMR, oncostatin M receptor
基因家族：Fibronectin type III domain containing
别名：OSMRB; OSMRbeta
全称：Oncostatin-M-specific receptor subunit beta

OSMR 分子靶点综述

抑瘤素M受体（Onconstatin M receptor, OSMR）是白细胞介素-6受体家族成员之一，该家族执行多种细胞功能，在炎症反应，代谢性疾病及细胞生长分化等生物学过程中起着重要作用。OSMR与gp130结合形成对OSM具有高亲和度的受体。在胃癌、结直肠癌、乳腺癌及胶质瘤等癌症样本中均可检测到OSM及OSMR的过度表达，因此靶向 OSMR 是一种治疗各种癌症以及皮肤疾病的重要治疗手段。

人 Human OSMR 分子靶点信息

分子名：OSMR, oncostatin M receptor
别称：
- IL-31 receptor subunit beta
- IL-31R subunit beta
- IL-31R-beta
- IL-31RB
- interleukin-31 receptor subunit beta
- MGC150626
- MGC150627
- MGC75127
- oncostatin-M specific receptor beta subunit
- oncostatin-M-specific receptor subunit beta
- OSMRB
- OSMRbeta
- PLCA1
基因序列：NCBI_Gene: 9180
蛋白序列：UniProtKB: Q99650

人 Human OSMR靶点分子功能（预测）

Enables growth factor binding activity. Contributes to oncostatin-M receptor activity. Involved in oncostatin-M-mediated signaling pathway and positive regulation of cell population proliferation. Part of apical plasma membrane and oncostatin-M receptor complex. Implicated in primary localized cutaneous amyloidosis 1.