EK1R01

Human Resistin ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

分子靶点：RETN, resistin, ADSF
种属：人 (Human)
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：50 μL
灵敏度：2.67 pg/mL
检测范围：31.25 pg/mL - 2000 pg/mL
回收率：85% - 108%

在售SKU:70-EK1R01-48, 70-EK1R01-96

¥<\/span>1,600.00<\/bdi><\/span><\/span>","sku":"70-EK1R01-48","variation_description":"","variation_id":10473,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"},{"attributes":{"attribute_size":"96T"},"availability_html":"","backorders_allowed":false,"dimensions":{"length":"","width":"","height":""},"dimensions_html":"N\/A","display_price":2650,"display_regular_price":2650,"image":{"title":"ELISA-1.jpg","caption":"","url":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","alt":"","src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","srcset":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg 800w, https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1-768x576.jpg 768w","sizes":"(max-width: 800px) 100vw, 800px","full_src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","full_src_w":800,"full_src_h":600,"gallery_thumbnail_src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1-100x100.jpg","gallery_thumbnail_src_w":100,"gallery_thumbnail_src_h":100,"thumb_src":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg","thumb_src_w":800,"thumb_src_h":600,"src_w":800,"src_h":600},"image_id":5986,"is_downloadable":false,"is_in_stock":true,"is_purchasable":true,"is_sold_individually":"no","is_virtual":false,"max_qty":"","min_qty":1,"price_html":"¥<\/span>2,650.00<\/bdi><\/span><\/span>","sku":"70-EK1R01-96","variation_description":"","variation_id":10474,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"}]">

Size
库存号

描述

文章目录[隐藏]

分子信息
RETN 分子靶点信息概述
RETN 分子靶点综述
- 人 Human RETN 分子靶点信息
- 人 Human RETN靶点分子功能（预测）

商品名	Human Resistin ELISA Kit (人抵抗素 (Resistin) ELISA试剂盒)
检测方法	双抗夹心法
精密度	板内变异系数：4.6% - 5.9%；板间变异系数：5.0% - 6.9%
样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	50 μL
灵敏度	2.67 pg/mL
检测范围	31.25 pg/mL - 2000 pg/mL
回收率	85% - 108%
平均回收率	0.93
板式	96孔板，可拆
保存	试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。
运输条件	4℃蓝冰运输
组分	包被抗Resistin单克隆抗体的96孔聚苯乙烯酶标板人Resistin冻干标准品 Resistin检测抗体标准品稀释液检测缓冲液(10×) 底物(TMB) 终止液洗液(20×) 封板膜

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人Resistin抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的Resistin与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中Resistin的浓度成正比。加入终止液终止反应，在450 nm波长(参考波长570 - 630 nm)测定吸光度值。

Human Resistin ELISA Kit (人抵抗素 (Resistin) ELISA试剂盒) - 标准曲线 — 标准曲线

分子信息

概述人 RETN, resistin, ADSF 靶点信息

RETN 分子靶点信息概述

分子名：RETN, resistin
别名：FIZZ3; ADSF; RETN1

RETN 分子靶点综述

抵抗素(Resistin)是一种富含半胱氨酸的来源于脂肪的肽激素，在人类中由RETN基因编码。在灵长类动物、猪和狗中，Resistin是由免疫细胞和上皮细胞分泌的。而在啮齿类动物中，它是由脂肪组织分泌的。人Resistin前肽的长度为108个氨基酸残基，小鼠和大鼠的长度则为114个氨基酸残基，分子量大约为12.5kDa。Resistin加速了动脉中低密度脂蛋白的积累，增加了人们患心脏病的风险。它会不良影响他汀类药物的作用效果，这类药物主要是降低胆固醇，用来治疗和预防心血管疾病的。最近研究发现Resistin还参与炎症反应。Resistin确实具有促炎性细胞因子的功能，并且可以作为炎症疾病中的一个重要节点。Resistin是一种脂肪来源的激素（类似于细胞因子），关于它参与肥胖和II型糖尿病这一生理作用一直是备受争议的话题。

人 Human RETN 分子靶点信息

分子名：RETN, resistin
别称：
- adipose tissue-specific secretory factor
- ADSF
- C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1
- c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein
- cysteine-rich secreted protein A12-alpha-like 2
- cysteine-rich secreted protein FIZZ3
- FIZZ3
- found in inflammatory zone 3
- MGC126603
- MGC126609
- resistin delta2
- RETN1
- RSTN
- XCP1
基因序列：NCBI_Gene: 56729
蛋白序列：UniProtKB: Q9HD89

人 Human RETN靶点分子功能（预测）

Predicted to enable hormone activity. Predicted to be involved in several processes, including fat cell differentiation; negative regulation of feeding behavior; and positive regulation of cell communication. Located in extracellular exosome. Implicated in hypertension; hypertrophic cardiomyopathy; obesity; and type 2 diabetes mellitus. Biomarker of several diseases, including diabetes mellitus (multiple); diabetic neuropathy; heart disease (multiple); kidney failure (multiple); and systemic lupus erythematosus.