EK108EGA

EasyGo!™ Human IL-8 One-Step ELISA Kit 检测试剂盒（酶联免疫吸附法）

¥2,190.00 – ¥3,650.00

说明书

分子靶点：CXCL8, IL-8, GCP1, NAP1
种属：人 (Human)
样本类型：血清，血浆
检测样本体积：100 μL（稀释液）
灵敏度：3.85 pg/mL
检测范围：15.625 pg/mL - 1000 pg/mL
回收率：85% - 122%

在售SKU:70-EK108EGA-48, 70-EK108EGA-96, EK108EGA, 人白细胞介素8, 白细胞介素8, 白细胞介素, 人, 白介素, 8, 一步法, 一步法ELISA, 一步法试剂盒, 一步法ELISA试剂盒

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Size
库存号

描述

商品名	EasyGo!™ Human IL-8 One-Step ELISA Kit 检测试剂盒（酶联免疫吸附法）
检测方法	双抗夹心法
精密度	板内变异系数：6.1% - 9.5%；板间变异系数：8.9% - 9.8%
样本类型	血清，血浆
检测样本体积	100 μL（稀释液）
灵敏度	3.85 pg/mL
检测范围	15.625 pg/mL - 1000 pg/mL
回收率	85% - 122%
平均回收率	1.02
板式	96孔板，可拆
保存	试剂盒未拆开，2 - 8℃保存。已拆开，标准品-20℃保存，其它2 - 8℃保存。
运输条件	4℃蓝冰运输
组分	酶标板标准品标准品稀释液显色底物终止液 20×洗液

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上，酶标板孔中预先加入生物素标记的微球和辣根过氧化物酶微球。酶标板孔中加入标准品和待测样本，经过孵育，样本中存在的待测物质与捕获抗体和检测抗体结合。洗涤去除未结合的物质后，加入显色底物（TMB），避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应，在 450 nm 波长 (参考波长 5630 nm) 测定吸光度值。

EasyGo!™ Human IL-8 One-Step ELISA Kit EasyGo!™ 人白细胞介素8 (IL-8) 一步法酶联免疫吸附测定试剂盒 - 标准曲线 — 标准曲线

分子信息

概述人 CXCL8, IL-8, GCP1, NAP1 靶点信息

CXCL8 分子靶点信息概述

分子名：CXCL8, C-X-C motif chemokine ligand 8
基因家族：Chemokine ligands; Interleukins
别名：SCYB8; LUCT; LECT; MDNCF; TSG-1; IL-8; NAP-1; 3-10C; MONAP; AMCF-I; LYNAP; NAF; b-ENAP; GCP-1; K60; GCP1; NAP1
曾用名：IL8
全称：neutrophil-activating peptide 1; granulocyte chemotactic protein 1; monocyte-derived neutrophil chemotactic factor; lung giant cell carcinoma-derived chemotactic protein; tumor necrosis factor-induced gene 1; monocyte-derived neutrophil-activating peptide; lymphocyte derived neutrophil activating peptide; beta endothelial cell-derived neutrophil activating peptide; alveolar macrophage chemotactic factor I; interleukin 8; chemokine (C-X-C motif) ligand 8

CXCL8 分子靶点综述

白细胞介素8(IL-8)是由巨噬细胞和其它类型细胞如上皮细胞、气道平滑肌细胞和内皮细胞产生的趋化因子，在人类中，由IL8基因编码。IL-8可有效促进血管生成，在细支气管炎的发病机制中起重要作用。IL-8可通过对中性粒细胞的召集和脱颗粒来实现对炎症反应的调节，可作为结肠癌细胞株的自分泌生长因子来作用于结肠直肠癌。高水平的IL-8可减少精神分裂症患者抗精神病药的阳性反应。另外，IL-8与肥胖和囊性纤维化的发病机制也相关。

人 Human CXCL8 分子靶点信息

分子名：CXCL8, C-X-C motif chemokine ligand 8
别称：
- alveolar macrophage chemotactic factor I
- beta endothelial cell-derived neutrophil activating peptide
- beta-thromboglobulin-like protein
- C-X-C motif chemokine 8
- chemokine (C-X-C motif) ligand 8
- emoctakin
- GCP-1
- GCP1
- granulocyte chemotactic protein 1
- IL8
- interleukin 8
- interleukin-8
- LECT
- LUCT
- lung giant cell carcinoma-derived chemotactic protein
- lymphocyte derived neutrophil activating peptide
- lymphocyte-derived neutrophil-activating factor
- LYNAP
- MDNCF
- MONAP
- monocyte-derived neutrophil chemotactic factor
- monocyte-derived neutrophil-activating peptide
- NAF
- NAP-1
- NAP1
- neutrophil-activating peptide 1
- SCYB8
- small inducible cytokine subfamily B, member 8
- T cell chemotactic factor
- T-cell chemotactic factor
- tumor necrosis factor-induced gene 1
基因序列：NCBI_Gene: 3576
蛋白序列：UniProtKB: P10145

人 Human CXCL8靶点分子功能（预测）

Enables chemokine activity and interleukin-8 receptor binding activity. Involved in several processes, including cellular response to cytokine stimulus; induction of positive chemotaxis; and neutrophil chemotaxis. Acts upstream of or within negative regulation of cell adhesion molecule production; positive regulation of cellular biosynthetic process; and regulation of gene expression. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Implicated in several diseases, including autoimmune uveitis; bacterial gastritis; gastrointestinal system cancer (multiple); trachoma; and urinary tract infection. Biomarker of several diseases, including chikungunya; cholestasis (multiple); cystic fibrosis; liver disease (multiple); and tuberculosis (multiple).