EK110EG

EasyGo!™ Human IL-10 One-Step ELISA Kit 检测试剂盒（酶联免疫吸附法）

¥2,190.00 – ¥3,650.00

说明书

分子靶点：IL10, CSIF, TGIF
种属：人 (Human)
样本类型：血清，血浆，DMEM细胞培养上清
检测样本体积：血清/血浆：10 μL；DMEM细胞培养上清：100 μL
灵敏度：11.71 pg/mL
检测范围：15.63 pg/mL - 1000 pg/mL
回收率：90% - 107%

在售SKU:70-EK110EG-48, 70-EK110EG-96, EK110EG, 一步法, 一步法ELISA, 一步法试剂盒, 一步法ELISA试剂盒, 人白细胞介素10, 白细胞介素10, 白细胞介素, 10, 白介素

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Size
库存号

描述

文章目录[隐藏]

分子信息
IL10 分子靶点信息概述
IL10 分子靶点综述
- 人 Human IL10 分子靶点信息
- 人 Human IL10靶点分子功能（预测）

商品名	EasyGo!™ Human IL-10 One-Step ELISA Kit检测试剂盒（酶联免疫吸附法）
检测方法	一步法
精密度	板内变异系数：3.9% - 5.7%；板间变异系数：4.5% - 7.3%
样本类型	血清，血浆，DMEM细胞培养上清
检测样本体积	血清/血浆：10 μL；DMEM细胞培养上清：100 μL
灵敏度	11.71 pg/mL
检测范围	15.63 pg/mL - 1000 pg/mL
回收率	90% - 107%
平均回收率	0.91
板式	96孔板，可拆
保存	试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。
运输条件	4℃蓝冰运输
组分	含微球的预包被酶标板标准品标准品稀释液显色底物终止液 20×洗液

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上，酶标板孔中预先加入辣根过氧化物酶标记的检测抗体微球。酶标板孔中加入标准品和待测样本，经过孵育，样本中存在的待测物质与捕获抗体和检测抗体结合。洗涤去除未结合的物质后，加入显色底物（TMB），避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应，在 450nm 波长(参考波长 570 - 630 nm)测定吸光度值。

EasyGo!™ Human IL-10 One-Step ELISA Kit检测试剂盒（酶联免疫吸附法）- 标准曲线 — 标准曲线

分子信息

概述人 IL10, CSIF, TGIF 靶点信息

IL10 分子靶点信息概述

分子名：IL10, interleukin 10
基因家族：Interleukins
别名：CSIF; TGIF; IL10A; IL-10
全称：cytokine synthesis inhibitory factor; T-cell growth inhibitory factor

IL10 分子靶点综述

白细胞介素10(IL-10)是由2个长178个氨基酸的亚基构成的同源二聚体。在人类中，它由位于1号染色体的IL-10基因编码，由5个外显子组成。IL-10主要由单核细胞分泌，淋巴细胞、II型辅助性T细胞(Th2)、肥大细胞、CD4+CD25+Foxp3+调节性T细胞和部分活化的T细胞和B细胞分泌较少。它对免疫调控和炎症具有多种效应。它下调巨噬细胞的Th1细胞因子、II类MHC抗原和共刺激分子。它还能增强B细胞存活、增殖和抗体分泌。IL-10能阻断NF-κB活性，并参与JAK-STAT信号通路调控。IL-10的免疫抑制特性提示其可能应用于临床，抑制器官移植后的排斥。IL-10还具有强烈的消炎特性。

人 Human IL10 分子靶点信息

分子名：IL10, interleukin 10
别称：
- CSIF
- cytokine synthesis inhibitory factor
- GVHDS
- IL-10
- IL10A
- interleukin-10
- MGC126450
- MGC126451
- T-cell growth inhibitory factor
- TGIF
基因序列：NCBI_Gene: 3586
蛋白序列：UniProtKB: P22301

人 Human IL10靶点分子功能（预测）

Enables protein dimerization activity. Involved in several processes, including negative regulation of cellular catabolic process; regulation of gene expression; and regulation of signal transduction. Acts upstream of or within several processes, including negative regulation of B cell proliferation; positive regulation of B cell apoptotic process; and positive regulation of signaling receptor activity. Located in extracellular space. Implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Biomarker of several diseases, including autoimmune disease (multiple); diabetes mellitus (multiple); eye disease (multiple); female reproductive organ cancer (multiple); and hematologic cancer (multiple).