EK1341

Human DLL1 ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

分子靶点：DLL1, δ样蛋白1
种属：人 (Human)
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：100 μL (稀释液)
灵敏度：9.49 pg/mL
检测范围：23.44 pg/mL - 1500 pg/mL
回收率：83% - 107%

在售SKU:70-EK1341-48, 70-EK1341-96, δ, δ样蛋白, δ 样蛋白, δ样蛋白1

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文章目录[隐藏]

DLL1 分子靶点信息概述
DLL1 分子靶点综述
DLL1, delta like canonical Notch ligand 1 分子靶点种属信息
- 人 Human DLL1 分子靶点信息
- 人 Human DLL1靶点分子功能（预测）

商品名	Human DLL1 ELISA Kit 人δ样蛋白1 (Human DLL1) ELISA试剂盒
检测方法	双抗夹心法
精密度	板内变异系数：7.0 % - 7.9%；板间变异系数：5.8 % - 7.2%
样本类型	血清、血浆，细胞培养上清及其他生物学样本
检测样本体积	100 μL (稀释液)
灵敏度	9.49 pg/mL
检测范围	23.44 pg/mL - 1500 pg/mL
回收率	83% - 107%
平均回收率	0.95
板式	96孔板，可拆
保存	试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。
运输条件	4℃蓝冰运输
组分	包被小鼠抗人DLL1捕获抗体的96孔聚苯乙烯酶标板 Human DLL1冻干标准品 Human DLL1检测抗体 Streptavidin-HRP 检测缓冲液(10×) 底物(TMB) 终止液洗液(20×) 封板膜标准品稀释液

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人DLL1抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的 DLL1与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物 TMB，避光显色。颜色反应的深浅与样本中 DLL1 的浓度成正比。加入终止液终止反应，在450 nm 波长(参考波长570 - 630 nm)测定吸光度值。

Human DLL1 ELISA Kit 人δ样蛋白1 (Human DLL1) ELISA试剂盒 - 标准曲线 — 标准曲线

DLL1 分子靶点信息概述

分子名：DLL1, delta like canonical Notch ligand 1
别名：delta (Drosophila)-like 1; delta-like 1 (Drosophila)

DLL1 分子靶点综述

DLL1 (Delta-like protein 1，δ样蛋白1)是Notch配体的跨膜糖蛋白。它在中枢神经系统的形态发生、椎间关节的形成、内耳毛细胞的发育和形成以及动脉的形成中起重要作用。DLL1 参与调节神经、胰腺和肌原祖细胞、T淋巴细胞和B淋巴细胞的稳态和分化。DLL1在许多癌症中过表达，与肿瘤的发生相关。DLL1的胞外区域可以从细胞表面脱落，胞内结构域可以被γ-分泌酶剪切，转移到细胞核，进而调控基因转录。

DLL1, delta like canonical Notch ligand 1 分子靶点种属信息

人 Human

人 Human DLL1 分子靶点信息

分子名：DLL1, delta like canonical Notch ligand 1
别称：
- Delta
- delta-like 1 (Drosophila)
- delta-like 1 protein
- delta-like protein 1
- DELTA1
- DL1
- drosophila Delta homolog 1
- H-Delta-1
- NEDBAS
基因序列：NCBI_Gene: 28514
蛋白序列：UniProtKB: O00548

人 Human DLL1靶点分子功能（预测）

Enables Notch binding activity and Tat protein binding activity. Involved in Notch signaling pathway; negative regulation of interleukin-10 production; and neuronal stem cell population maintenance. Predicted to be located in adherens junction; apical plasma membrane; and membrane raft. Predicted to be active in plasma membrane. Biomarker of temporal arteritis.