EK1323

Human BMP-4 ELISA Kit检测试剂盒（酶联免疫吸附法）

¥2,000.00 – ¥3,400.00

分子靶点：BMP4, BMP2B
种属：人 (Human)
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：100 μL(稀释液)
灵敏度：0.30 pg/mL
检测范围：3.91 pg/mL - 250 pg/mL
回收率：76% - 103%

在售SKU:70-EK1323-48, 70-EK1323-96

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库存号

描述

文章目录[隐藏]

分子信息
BMP4 分子靶点信息概述
BMP4 分子靶点综述
- 人 Human BMP4 分子靶点信息
- 人 Human BMP4靶点分子功能（预测）

商品名	Human BMP-4 ELISA Kit (人骨形态发生蛋白4 (BMP-6) ELISA试剂盒)
检测方法	双抗夹心法
精密度	板内变异系数：1.3% - 3.5%；板间变异系数：4.9%-8.7%
样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	100 μL(稀释液)
灵敏度	0.30 pg/mL
检测范围	3.91 pg/mL - 250 pg/mL
回收率	76% - 103%
平均回收率	0.92
板式	96孔板，可拆
保存	试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。
运输条件	4℃蓝冰运输
组分	包被抗BMP-9单克隆抗体的96孔聚苯乙烯酶标板人BMP-9冻干标准品 Angiotensinogen/AGT/ SerpinA8检测抗体标准品稀释液检测缓冲液(10×) 底物(TMB) 终止液洗液(20×) 封板膜

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人BMP-4抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、检测样本和辣根过氧化物酶标记的检测抗体，经过孵育，样本中存在的BMP-4与固相抗体和检测抗体结合。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中BMP-4的浓度成正比。加入终止液终止反应，在450 nm波长(参考波长570 - 632 nm)测定吸光度值。

Human BMP-4 ELISA Kit (人骨形态发生蛋白4 (BMP-6) ELISA试剂盒) - 标准曲线 — 标准曲线

分子信息

概述人 BMP4, BMP2B 靶点信息

BMP4 分子靶点信息概述

分子名：BMP4, bone morphogenetic protein 4
基因家族：Bone morphogenetic proteins
曾用名：BMP2B

BMP4 分子靶点综述

BMP是分泌的信号分子，包含TGF-β超家族的一个亚家族，最初被鉴定为软骨和骨形成的调节剂。通常，BMP与各种组织和器官的胚胎发生和形态发生有关。BMP-2，BMP-4和BMP-7，在中胚层胚层的造血组织规范中起作用。它们调节来自成年和新生儿来源的高度纯化的原始人类造血细胞的增殖和分化。BMP-4，也称为骨形态发生蛋白4，它形成二硫键连接的同型二聚体。已证明BMP-4也参与交感神经元的分化。它增强了神经c细胞培养物中肾上腺素能交感神经元的形成。

人 Human BMP4 分子靶点信息

分子名：BMP4, bone morphogenetic protein 4
别称：
- BMP-2B
- BMP-4
- BMP2B
- BMP2B1
- bone morphogenetic protein 2B
- bone morphogenetic protein 4 preproprotein
- MCOPS6
- OFC11
- ZYME
基因序列：NCBI_Gene: 652
蛋白序列：UniProtKB: P12644

人 Human BMP4靶点分子功能（预测）

Enables BMP receptor binding activity; co-receptor binding activity; and receptor ligand activity. Involved in several processes, including animal organ development; negative regulation of cell population proliferation; and transmembrane receptor protein serine/threonine kinase signaling pathway. Acts upstream of or within several processes, including positive regulation of osteoblast differentiation; regulation of transcription by RNA polymerase II; and respiratory system development. Located in extracellular space. Implicated in several diseases, including CAKUT (multiple); cleft lip; orofacial cleft 11; ossification of the posterior longitudinal ligament of spine; and otosclerosis. Biomarker of several diseases, including Barrett's esophagus; eye disease (multiple); myositis ossificans; progressive osseous heteroplasia; and prolactinoma.