EK1254

Human CXCL16 ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

分子靶点：CXCL16, SRPSOX
种属：人 (Human)
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：100 μL
灵敏度：1.09 pg/mL
检测范围：3.13 pg/mL - 200 pg/mL
回收率：81% - 105%

在售SKU:70-EK1254-48, 70-EK1254-96

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库存号

描述

文章目录[隐藏]

分子信息
CXCL16 分子靶点信息概述
CXCL16 分子靶点综述
- 人 Human CXCL16 分子靶点信息
- 人 Human CXCL16靶点分子功能（预测）

商品名	Human CXCL16 ELISA Kit (人 CXCL16 ELISA试剂盒)
检测方法	双抗夹心法
精密度	板内变异系数：4.3% - 5.7%；板间变异系数：5.5% - 7.3%
样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	100 μL
灵敏度	1.09 pg/mL
检测范围	3.13 pg/mL - 200 pg/mL
回收率	81% - 105%
平均回收率	0.98
板式	96孔板，可拆
保存	试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。
运输条件	4℃蓝冰运输
组分	包被抗CXCL16单克隆抗体的96孔聚苯乙烯酶标板人CXCL16冻干标准品 CXCL16检测抗体标准品稀释液检测缓冲液(10×) 底物(TMB) 终止液洗液(20×) 封板膜

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人CXCL16抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品和待测样本，经过孵育，样本中存在的CXCL16与固相抗体结合。洗涤去除未结合的物质后，加入生物素化的检测抗体孵育。洗涤去除未结合的生物素化的抗体，加入辣根过氧化物酶标记的链霉亲和素 (Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中CXCL16的浓度成正比。加入终止液终止反应，在450 nm波长(参考波长570 - 630 nm)测定吸光度值。

Human CXCL16 ELISA Kit (人 CXCL16 ELISA试剂盒) - 标准曲线 — 标准曲线

分子信息

概述人 CXCL16, SRPSOX 靶点信息

CXCL16 分子靶点信息概述

分子名：CXCL16, C-X-C motif chemokine ligand 16
基因家族：Chemokine ligands; Scavenger receptors
别名：SR-PSOX; CXCLG16; SRPSOX
全称：CXC chemokine ligand 16; chemokine (C-X-C motif) ligand 16

CXCL16 分子靶点综述

趋化因子(C-X-C 基序)配体 16(CXCL16)是属于 CXC 趋化因子家族的一种小分子量细胞因子，由 254 个氨基酸组成，是一种 I 型膜蛋白。人类 CXCL16 的基因位于 17 号染色体上。CXCL16 是由淋巴器官 T 细胞区内的树突状细胞和脾脏红髓内的细胞产生的。炎症细胞因子 IFN-γ和 TNF-α 可诱导 CXCL16 的表达。CXCL16 与趋化因子受体 CXCR6(也被称为 Bonzo)相互作用。注射叶酸可迫使 CXCL 16 发生甲基化，诱导 CXCL 16 基因启动子在结肠、回肠和肺部产生高水平的甲基化，同时也使 iNKT 细胞在这些组织中积聚。

人 Human CXCL16 分子靶点信息

分子名：CXCL16, C-X-C motif chemokine ligand 16
别称：
- C-X-C motif chemokine 16
- chemokine (C-X-C motif) ligand 16
- CXC chemokine ligand 16
- CXCLG16
- scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
- small-inducible cytokine B16
- SR-PSOX
- SRPSOX
- transmembrane chemokine CXCL16
基因序列：NCBI_Gene: 58191
蛋白序列：UniProtKB: Q9H2A7

人 Human CXCL16靶点分子功能（预测）

Enables chemokine activity. Involved in several processes, including positive regulation of cell growth; response to interferon-gamma; and response to tumor necrosis factor. Located in extracellular space. Biomarker of COVID-19 and systemic scleroderma.