Mir-10b Inhibits Apoptosis and Promotes Proliferation and Invasion of Endometrial Cancer Cells Via Targeting Hoxb3

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  • 作者：Chen, H., Fan, Y., Xu, W., Chen, J., Xu, C., Wei, X., Fang, D. & Feng, Y.
  • 期刊：Cancer biotherapy & radiopharmaceuticals 31, 225-231 (2016)
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MicroRNAs are small RNA that are tightly interrelated with the initiation, development, and metastasis of cancers. Studies have shown that miR-10b is increased in various cancers. However, the underlying mechanisms of miR-10b in the occurrence and metastasis of endometrial cancer are poorly understood. To investigate its roles and correlations with Homeobox box 3 (HOXB3) in endometrial cancer, cancer tissues and adjacent normal endometrium tissues from 20 patients with endometrial cancer were studied. miR-10b expression was significantly up-regulated (p?文章引用产品