Tm4sf1 Regulates Apoptosis, Cell Cycle and Ros Metabolism Via the Pparγ-Sirt1 Feedback Loop in Human Bladder Cancer Cells

  • 类型：
  • 作者：Cao, R., Wang, G., Qian, K., Chen, L., Ju, L., Qian, G., Wu, C. L., Dan, H. C., Jiang, W., Wu, M., Xiao, Y. & Wang, X.
  • 期刊：Cancer letters 414, 278-293 (2018)
  • 阅读原文

Transmembrane-4-L-Six-Family-1 (TM4SF1) is a member of the L6 family and functions as a signal transducer to regulate cell development, growth and motility. Here we show that TM4SF1 is strongly upregulated in human muscle invasive bladder cancer (MIBC) tissues, corroborating the bioinformatical results of transcriptome analysis. Moreover, tissue microarray (TMA) shows significant correlations (p?

待确认